About Decapinol™

Decapinol is registered in the EU and in the USA as a medical device.

How Decapinol works

Decapinol has a novel mode of action. It works at the interface between dental plaque bacteria and the surface of the teeth and gums. Decapinol reduces adherence of the bacterial plaque to the oral surfaces, and also of bacteria to each other1. This mode of action not only reduces the formation of new plaque but also breaks up existing plaque, making it easier to remove with normal toothbrushing. By reducing the presence of plaque, the amount of bacterial toxins released into the gum is reduced. The end result is a reduction in both plaque and gingivitis.

Decapinol’s efficacy and safety in the reduction of plaque and treatment of gingivitis has been demonstrated in extensive clinical studies carried out by leading periodontists.

 

Not an anti-bacterial agent

Decapinol’s mode of action is different from that of other therapeutic agents for dental plaque control and the treatment of gingivitis, which work by killing oral bacteria. Decapinol has low antimicrobial activity against the normal primary colonising oral flora. Decapinol provides an intelligent and desirable method of treating gingivitis, in which the ecological balance of oral flora is maintained, avoiding indiscriminate killing of all oral bacteria.

Lack of dark staining

 
Decapinol does not cause the semi-permanent dark tooth-staining that occurs with chlorhexidine, and which often restricts the duration of use of chlorhexidine products in the treatment and prevention of gingivitis. Chlorhexidine is the key ingredient of most anti-gingivitis products currently recommended by dentists.

 

Lack of interaction with toothpaste

The efficacy of Decapinol is not reduced by SLS, a common ingredient of toothpaste, unlike chlorhexidine².

 

How to use Decapinol

 
Twice a day after normal toothbrushing, rinse the mouth with 10ml of Decapinol mouthwash for around 1 minute.

 

1	Klinge B, Matsson L, Attstrom R et al. Effect of local application of delmopinol hydrochloride on developing and early established supragingival plaque in humans. J Clin Periodontol 1996; 23: 542-547
2	Barkvoll P, Rölla G, Svendsen AK. Interaction between chlorhexidine digluconate and sodium lauryl sulphate in vivo. J Clin Periodontol 1989; 16:593-595